Regent Philippe of Orléans acquired the Madonna of the House of Orléans by Raphaël and it remained in the collection of Orléans until the Revolution. In 1791, Philippe-Egalite, drowning in debt, sold all of his Italian paintings. The Madonna moved to England. The Duke of Aumale bought it back in 1869 because of its family origin. It is a wonderful example of the private devotional virgins Raphaël dedicated himself to during his youth, and very medieval in its iconography. The "tyriana" placed in the background is a cure for snakebites, and a symbol of Evil. The tyriana and the apple therefore act as an image of the Christ's sin redemption.